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L-Proline CAS 147-85-3 | Stable Chemical Applications

  • L-Proline (CAS 147-85-3) is a high-purity amino acid with unique cyclic structure, offering excellent stability and compatibility. Widely used in nutrition, pharmaceuticals, cosmetics, and fine chemical synthesis....
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Detailed introduction



Why L-Proline Matters in Modern Formulations

L-Proline is more than a standard amino acid.Its unique cyclic structure gives it a functional profile that stands apart from linear amino acids, making it especially valuable in formulations where stability, reactivity, and bio-compatibility are critical.In many industries, L-Proline is selected not only for its nutritional role, but because it improves system performance, supports downstream reactions, and integrates smoothly into complex formulations.

Product Overview

Structural Advantage 

Unlike most amino acids, L-Proline contains a secondary amine.
This allows it to:

  • Participate efficiently in chiral reactions

  • Enhance reaction selectivity in fine chemical synthesis

  • Perform reliably as a building block in advanced formulations

For chemical buyers, this means higher reaction efficiency and fewer side products.

Excellent Compatibility Across Systems

L-Proline works well in:

  • Aqueous systems

  • Fermentation processes

  • Multi-component blends

It does not easily interfere with salts, buffers, or other amino acids, which reduces formulation risk during scale-up.

Stability You Can Rely On

Many amino acids are sensitive to humidity or storage conditions.
L-Proline offers:

  • Good shelf stability

  • Low hygroscopicity

  • Consistent performance during transport and long-term storage

This makes it especially attractive for export-oriented supply chains.

Where Customers Actually Use L-Proline

Food & Nutrition Developers

L-Proline is often selected when:

  • Formulations target collagen-related nutrition

  • Stability during processing is important

  • A clean, well-recognized amino acid profile is required

Pharmaceutical & API Manufacturers

Used as:

  • A synthetic intermediate

  • A component in amino acid injections or blends

  • A chiral source in stereoselective synthesis

Its predictable behavior helps reduce batch variation.

Cosmetic Formulators

Chosen for:

  • Skin-conditioning systems

  • Moisturizing and barrier-support products

  • Formulations focused on skin elasticity and repair concepts

L-Proline integrates smoothly without affecting product texture or odor.

Typical Product Specifications

ItemTypical Value
AppearanceWhite crystalline powder
Assay≥ 98.5%
Optical Rotation−84° to −86°
Loss on Drying≤ 0.3%
SolubilityFreely soluble in water
Heavy Metals≤ 10 ppm

Packaging & Supply

25 kg fiber drums / paper bags with PE liner

Small packs available for trial orders

OEM labeling supported

Stable export supply

FAQ

Q1:Why choose L-Proline instead of other amino acids?

Because its cyclic structure offers unique reactivity, better stability, and broader application flexibility.

Q2:Is it suitable for both formulation and synthesis?

Yes. It is widely used in both finished formulations and as an intermediate.

Q3:Can documents be provided for audits?

COA, MSDS, and technical data are available.

Feel free to contact us

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  • Phone:+86-531-88752665
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