CAS number：7681-93-8
molecular formula：C33H47NO13
molecular weight：665.73
EINECS number：231-683-5

English synonyms

NataMycin, A 5283, Delvolan, Delvocid, Myprozine, Natacyn, Natafucin, PiMafucin, PiMafugin, A5263, CL 12625, E235;Natamycin(FermentionProcess);(1R*,3S*,5R*,7R*,8E,12R*,14E,16E,18E,20E,22R*,24S*,25R*,26S*)]-22-[(3-Amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid;NATAMYCIN;PIMAFUCIN;PIMARICIN;PIMARICIN, STREPTOMYCES CHATTANOOGENSIS;antibiotica-5283

Related categories

Quaternary ammonium salts, phase transfer catalysts Phase Transfer Catalysts; fungal inhibitors; antibiotics; small molecule inhibitors; fungicides; microbial metabolites; medical raw materials; other raw materials; preservatives; antiseptic insecticides; food additives; medicine Raw material; natamycin; pharmaceutical and chemical industry; reference substance-impurity reference substance; reference substance; chemical reagent; traditional Chinese medicine reference substance; preservative-natamycin; other biochemical reagents; vitamin series; 1; Food Additives; Food & Feed ADDITIVES; Antifungal (Topical); Intermediates & Fine Chemicals; Pharmaceuticals; food additives; Biochemical reagents; Antibiotics; ERGOSTAT; antibiotic; Food additive; raw materials; ; Raw materials; Biological antiseptic; Pharmaceutical, pesticide and dye intermediates; Technical intermediates; Chemical reagents - veterinary raw materials; General biochemical reagents - antibiotics; Scientific research raw materials; Chemical reagents; Chemical raw materials - 1827181813;

Introduction

Natamycin, also known as pimaricin and natamycin, was first isolated from Streptomyces natalis in 1955, and its activity is far superior to that of sorbic acid. In June 1982, the U.S. FDA officially approved natamycin as a food preservative and classified it as a GRAS product. Natamycin is a highly effective inhibitor of mold, yeast and fungi. It is used to inhibit mold, yeast and fungi in food. It is very safe and reliable for the human body without affecting the flavor of the product. It is widely used in the world. For cheese, meat products, pastries, fruit juice and other foods. The product is refined from Streptomyces natalensis through submerged fermentation and multi-step extraction process, and its preparation is made by mixing 50% natamycin and 50% lactose.

Near white to creamy yellow powder, almost odorless and tasteless. Can contain 3mol of water. The melting point is 280°C (decomposition). Almost insoluble in water, slightly soluble in methanol, soluble in glacial acetic acid and dimethyl sulfoxide.

●  anti-fungal agent. It has good anti-mold effect when it is used on the surface of food exposed to the air where mold is easy to proliferate. Used in fermented cheese, it can selectively inhibit the reproduction of mold and allow bacteria to grow and metabolize normally.
The product should be stored in a well-sealed place, without direct sunlight, at <15°C.

●  An antifungal polyene antibiotic that inhibits fungal growth by binding specifically to ergosterol. Unlike nystatin and filipinidine, natamycin does not alter cell membrane permeability.

●  Made by controlled fermentation of Streptomyces natalensis.

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