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      alpha-Bisabolol CAS 515-69-5

      • alpha-Bisabolol CAS 515-69-5...
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      Detailed introduction



      CAS number:515-69-5
      molecular formula:C15H26O
      molecular weight:222.37
      EINECS number:208-205-9

      English synonyms

      (R*, R*)-alpha, 4-Dimethyl-alpha-(4-methyl-3-pentyl)cyclohex-3-en-1-methanol;(R*,R*)-alpha-4-Dimethyl-alpha-(4-methyl-3-petenyl)-3-cyclohexene-1-methanol;α-bisabolol,6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol,dragosantol;3-Cyclohexene-1-methanol, .alpha.,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)-, (.alpha.R,1R)-rel-;6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepteno;alpha-Bisabalol;alpha-bisabolool;Camilol

      Related categories

      Chemical industry; organic chemical raw materials; cosmetic raw materials; pharmaceutical chemical raw materials; chemical raw materials; active ingredients; antibacterial and anti-inflammatory; daily chemical raw materials; raw materials; intermediates; organic chemicals; pharmaceutical raw materials; bisabolol; cosmetic raw materials; raw materials; organic chemicals raw materials; intermediates-chemical intermediates; pharmaceutical, pesticide and dye intermediates; organic intermediates; chemical materials; monomer fragrances; alcohols, aldehydes, ketones; chemical reagents; reference substances;Biochemistry;Terpenes;Terpenes (Others); 515-69-5

      Introduction

      Bisabolol, also known as sweet bisabolol and parsnipol, is one of the most abundant sesquiterpene compounds in nature. It has two structures, α-body and β-body, and its molecular formula is C15H26O . It is mainly found in chamomile essential oil, poplar essential oil, and certain essential oils of the genus Bitteria and sage.

      Chemical properties

      Melting point

      25°C

      Boiling point

      154-156°C

      Density

      0.93 g/mL at 20 °C(lit.)

      Refractive index

      n20/D 1.496

      Flash point

      135°C

      Storage conditions

      Refrigerator

      Solubility

      Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)

      Acidity coefficient(pKa)

      15.04±0.29(Predicted)

      Shape

      Liquid

      Color

      Clear Colourless

      Water solubility

      Soluble in alcohol, natural, mineral and synthetic oils. Insoluble in water.

      Merck 

      14,1241

      BRN 

      5733954

      Stability

      Stable. Combustible. Incompatible with strong oxidizing agents.

      CAS database

      515-69-5(CAS DataBase Reference)

      Use

      ●  Alpha-bisabolol can be used for healing ulcers, dissolving gallstones, etc., and has the functions of analgesia, anti-inflammatory, and antibacterial. In recent years, α-bisabolol has also been found to have various other biological activities, such as anti-mutation, inhibition of genetic damage, and demelanogenesis.

      ●  Bisabolol is mainly used in skin protection and skin care cosmetics. Bisabolol is used as an active ingredient to protect and care for sensitive skin. Bisabolol is suitable for use in sunscreen products, post-sun bath lotions, baby products and shaving in aftershave products. In addition, bisabolol can be used in oral hygiene products such as toothpaste and mouthwash.

      ●  1. Anti-inflammatory and antispasmodic effects. Natural bisabolol works twice as well as synthetics in this function. It can reduce the release of leukotriene LTB4 and interleukin IL-1α caused by PMA, and reduce the skin irritation caused by sodium hydroxide and SDS, thereby preventing and inhibiting inflammation.
      2. Alleviate irritation and analgesic repair effect. It has a skin care effect on allergic skin or children's skin care. It also protects the skin from daily tension and accelerates the skin healing process.
      If your skin is accidentally damaged by some "strong medicine", you can choose skin care products containing bisabolol as a repair product.
      3. Calming and anti-perspirant effects. Therefore, it is often used in sunscreen products and ointments for the treatment of sunburn and sunburn.
      4. Broad-spectrum antibacterial properties. Adding to toothpaste and mouthwash can reduce plaque and gum irritation, prevent bad breath, and refresh breath.
      5. The aroma is light and pleasant. Bisabolol is also a stabilizer with good stability, so it is also widely used in flavors and fragrances.
      6. High permeability of the cortex. The effect of bisabolol is dozens of times that of commonly used penetrants. It can be used as the main agent or auxiliary agent to prevent and treat skin diseases such as acne, and it also has a conditioning effect on the skin.
      7. Good stability. Therefore, it is very suitable for use in cosmetics. Bisabolol will not change color after long-term storage, nor will it seep out of plastic containers, and there will be no problems in using it.


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