CAS number：439685-79-7
molecular formula：C8H16O5
molecular weight：192.21
EINECS number：456-880-5

English synonyms:

(2S,3R,4S,5R)-2-(2-hydroxypropyl)oxane-3,4,5-triol;Nano liposomal hydroxypripyl tetrahydropyrantriol;Retinol Pro+Pro-xylane;Pro-Xylane,Puri-Xylane;HYDROXYPROPYL TETRAHYDROPYRANTRIOL;Puri-Xylane;Nano Liposomal HYDROXYPROPYL TETRAHYDROPYRANTRIOL;Tetrahydropyrantriol

Related categories:

Alkaloids; Intermediates; Plant Extracts; Anti-aging; Pharmaceutical Raw Materials; Anti-aging and Wrinkle Removal; Chemical Intermediates; Cosmetic Additives; Cosmetics; Bosein;Organic chemical raw materials;Organic intermediates;Chemicals;Cosmetic peptides;Cosmetic functional raw material additives-Bosein;New product series;Cosmetic active raw materials;Raw material intermediates;API;Fermented products;Anti-aging and anti-oxidation;Daily chemicals and cosmetic active molecules; chemical raw materials; chemicals; raw materials; daily chemical raw materials; additives; organic raw materials; spot; sugars

Introduction：

Puri-Xylane, commonly known as Boseine, is a xylose derivative with anti-aging actives, which can promote the synthesis of collagen, make the skin stronger and more elastic, improve fine lines on the neck, prevent senescence. Boseine is a mixture of glycoproteins derived from xylose. Since xylose is abundantly present in beech trees, it has the ability to promote the production of glycosaminoglycans, namely glycosaminoglycans (GAGs). As Boseine extracted from beech trees, its effect is similar to that of xylose.

●  1. Stimulates the production and construction of GAGs (Glupolysaccharide extracellular matrix) (e.g. gelatinous proteinaceous network and sugars that act as scaffolds and intercellular shock absorbers) to gel the matrix and increase cell and skin firmness .
2. It acts as a channel to guide repair molecules, such as proteins that allow cells to grow.
3. Use the activity of the extracellular matrix to send messages to young cells while re-stimulating aging cells.
4. Strengthen basement membrane function, reduce allergy and inflammation.
The skin-improving effect of Boseine is comprehensive, not only limited to the extracellular matrix, but also the connection between the matrix and cells, the density and firmness of the skin, and the promotion of type VI and Iv collagen self-generation. Along with niacinamide and tranexamic acid, Boseine is listed as Mr. Cai's favorite three multi-effect skin beautifying ingredients.

●  Boseine can induce the biosynthesis of GAGs mucopolysaccharide and PG proteoglycan in the superficial epidermis. The absence of GAGs and PG will lead to a decrease in skin water content and defense ability; it can effectively promote the epidermis-dermis tight junction and better fix the dermis layer. , the skin is stronger and more elastic; long-term use can effectively improve the wrinkles and fine lines of the face and neck, and promote the regeneration of damaged tissue.

●  1. Activation of glycosaminoglycan (GAGs) synthesis:
This high-tech ingredient, based on the principle of bionics, activates the synthesis of glycosaminoglycans (GAGs) from a sugar called xylose.
There are a large number of mucopolysaccharides between the extracellular matrix (ECM) of our skin, most of which are carbohydrate polymers (GAG) composed of uronic acid and aminoglycan, and these mucopolysaccharides play a very important role in the skin. Because mucopolysaccharides can absorb moisture and prevent skin moisture loss.
At the same time, because the mucopolysaccharide absorbs a lot of water, it can form a structure that can be imagined as a colloid composed of water. At the same time, the water absorption capacity of the molecular structure of these protein mucopolysaccharides GAGs makes the matrix network more elastic, which helps to improve the compactness of cells and enhance the elasticity of the skin. These are important factors that affect the elasticity and texture of the skin.
2. Stimulates the production of glycosaminoglycans (GAGs) in the skin:
Hydroxypropyltetrahydropyrantriol is a glycoprotein mixture that stimulates the production of cutaneous aminoglucans (GAGs).
GAGs are the main components of extracellular matrix, and hyaluronic acid contained in them is one of the main components of GAGs. Hyaluronic acid has a strong ability to absorb water and store water. It can be injected into the dermis layer to achieve the effect of filling and moisturizing the skin, and the skin is plump and elastic. Hyaluronic acid is also commonly used to fill sunken areas of the skin, including wrinkles.
In terms of skin structure, GAGS, the dermis of the skin mainly includes collagen, elastin, and extracellular matrix (containing GAGs).

●  The original synthetic route of Bosein is: a large amount of xylose (Xylose) extracted from beech as the main raw material, and acetylacetone (Acetylacetone) in an alkaline aqueous solution to undergo Knoevenagel condensation reaction (that is, a compound with active methylene groups). (such as malonate, β-ketoester, cyanoacetate, nitroacetate, etc.) under the catalysis of ammonia, amine or its carboxylate, it undergoes aldol condensation with aldehyde and ketone, and dehydration And obtain α, β-unsaturated compound reaction), generate 1-C-(beta-D-xylopyranosyl)-acetone. After that, it undergoes a reduction reaction with sodium borohydride to reduce the ketone carbonyl group in the product to obtain 1-C-(beta-D-xylopyranosyl)-2-hydroxy-propane, that is, Boseine ( Pro-xylane).

Team Presentation