CAS number：352-97-6
molecular formula：C3H7N3O2
molecular weight：117.11
EINECS number：206-529-5

English synonyms

N-Amidinoglycin;(Aminoiminomethyl)aminoacetic acid;GLYCOCYAMINE(GUANIDINOACETIC ACID)(P);Guanidineacetic acid,N-Amidinoglycine, N-Guanylglycine, Glycocyamine;Guanidineacetic acid 99%;Guanidineacetic acid,glucocyamine,Glycocyamine;BetacyaMine;NSC 1901

Related categories

Amino Acids; Amino Acids, Proteins and Nucleic Acids; Pharmaceutical Raw Materials; Guanidine; Nutritional Enhancers; Agricultural and Animal Drugs - Livestock Drugs; Organic Chemical Raw Materials; Feed Additives; Feed Raw Materials; Chemical Intermediates; Nutritional Supplements; Pharmaceutical Chemicals - Veterinary Drug Raw Materials; Food And feed additives - feed additives; other chemical products; API raw materials - veterinary drug raw materials; nutritional enhancers - amino acids; guanidine acetic acid; food additives; agricultural and veterinary raw materials; feed additives; raw materials; medical raw materials; Other chemical products; Pharmaceutical Intermediates; Intermediates & Fine Chemicals; Pharmaceuticals; Building Blocks; Chemical Synthesis; Guanidines; Nitrogen Compounds; Agent; chemical raw material; veterinary raw material; food additive; chemical industry; nutrition enhancer amino acid; additive; reference substance

Introduction

Guanidino Acetic acid (GAA) is the precursor of creatine in animals and participates in the regulation of energy metabolism in the body. As a new type of nutritional feed additive, guanidinoacetic acid has the functions of improving the growth performance, slaughtering and reproductive performance of pigs, chickens and other animals, and improving meat quality.

Chemical properties

Use

●  Guanidinoacetic acid is the precursor of creatine. Creatine phosphate, which contains high phosphate group transfer potential energy, is widely found in muscle and nerve tissues. It is the main energy supply substance in animal muscle tissue and can be used as food additives, organic synthesis intermediate.

Production method

●  S-ethylthiourea hydrobromide is generated by the reaction of thiourea and bromoethane, and then reacted with glycine to obtain guanidineacetic acid. Mix thiourea, ethyl bromide and absolute ethanol and warm in a water bath for 3 hours to dissolve all thiourea. Then distill off ethanol and excess bromoethane under reduced pressure, crystallize the residue, and dry to obtain S-ethylthiourea hydrobromide. Then add sodium hydroxide solution into the obtained S-ethylthiourea hydrobromide, and quickly add the hot solution made of glycine and water under cooling. After crystallization, diethyl ether was added and left overnight, the mixture was cooled in an ice bath for 2 h, and the diethyl ether layer was separated. Suction filtration, followed by washing with ice water, ethanol, ether, and air-dried to obtain the finished product.

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