CAS number：1405-41-0
molecular formula：C60H127N15O26S
molecular weight：1506.8
EINECS number：215-778-9

English synonyms

GENTAMICIN 2,5-SULFATE HYDRATE;Alcomicin, Bristagen, Cidomycin, Duragentam, Garamycin, Garasol,Genoptic, Gentacidin, Gentacin,Gentaglyde, Gentalyn, Gentamicin C Complex Citrate, Gentibioptal, Genticin, Gentocin, Gentogram, Gent-Ophtal, Getalline, GM sulfate;2-[4,6-Diamino-3-[3-amino-6-(1-methylaminoethyl)oxan-2-yl]oxy-2-hydroxy-cyclohexoxy]-5-methyl-4-methylamino-oxane-3,5-diol sulphate;Gentamycin sulfate;Gentamicin for peak identification;Gentamicin sulfate solution,1000ppm;Gentamicin sulfate solution,100ppm;Gentamicin Sulfate, 500X Solution

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Pharmaceutical intermediates; Raw materials; Small molecule inhibitors; Biochemistry; Solvents; Antibiotics; Antibiotics, alkaloids; Antibiotics; ;Chemical Reagents;Reference Substances;Intermediates;Pharmaceutical and Veterinary Drugs;Raw Material Intermediates-APIs;Fine Chemicals;Reagents;Veterinary Raw Materials;API API-Veterinary APIs;Medical Raw Materials;Interferes with Protein Synthesis;Mechanism of Action;Spectrum of Activity;AminoglycosidesResearch Essentials;Antibiotics G-MAntibiotics;Antibiotics Antibiotics;Core Bioreagents;Antibiotics G-MAnalytical Standards;GAntibiotics;Peptide Synthesis/Antibiotics;Oligosaccharides;APIs;Analytical Standards;GARAMYCIN;antibiotic;Aminoglycoside Standard Antibiotics; Products-standard products of traditional Chinese medicine; pharmaceutical raw materials; chemical intermediates; biochemical industry; additives; traditional Chinese medicine reference substances; chemical reagents; chemical raw materials; feed additives; Raw materials; Industrialization; Active Pharmaceutical Ingredients; All Inhibitors; Antibiotic Explorer; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; Antibiotics G-MSerum-free Media; Hybridoma Reagents Antibiotics; A - KAntibiotics; ;Hybridoma Platform;AminoglycosidesCell Culture;AntibioticsNeural Stem Cell Biology;AntibioticsStem Cell Expansion;Culture;Interferes with Protein SynthesisMore...Close ...;Neural Stem Cell Isolation/Expansion;Reagents and Supplements;Alphabetic;API's;Antibiotic and Antimicrobial Agents

Introduction

Gentamicin sulfate is an aminoglycoside antibiotic, which is a glycoside formed by aminocyclohexyl polyol and amino sugar. There are five basic centers in the gentamicin molecule, which is a basic compound, and the drug is the sulfate of gentamicin. Gentamicin is a complex of C components, the main components of which are C1, C2, C1a and C2a.

Chemical properties

Use

●  Used to treat sepsis, urinary tract infections, staph infections, endocarditis, and other conditions

●  Clinically used for sepsis, respiratory tract infection, biliary tract infection, suppurative peritonitis, intracranial infection, urinary tract infection caused by Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Shigella, Klebsiella, Proteus and other sensitive bacteria Infections and bacillary dysentery and other diseases.

●  Gentamicin binds to the 30S ribosomal subunit to cause codon misreading and blocks the transfer of peptidyl-tRNA from the acceptor site to the donor site. The bactericidal effect of gentamicin on Pseudomonas depends on binding to the outer membrane part of the cell membrane, displacing the existing cations, making the membrane unstable and forming cavities on the cell surface. Antimicrobial Spectrum: Gram-negative bacteria, Staphylococci and other Gram-positive bacteria.

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