CAS number：151-21-3
molecular formula：C12H25NaO4S
molecular weight：288.38
EINECS number：205-788-1

English synonyms

LAURYL SULFATE SODIUM SALT;LAURYL SODIUM SULFATE;LAURYL SULFATE, SODIUM;LAURYL SULFATE NA-SALT;IPC-SDS;DODECYLSULFURIC ACID SODIUM SALT;DODECYL SULFATE SODIUM;DODECYL SULFATE SODIUM SALT

Related categories

Detergents; Solvents; Genomics and Molecular Diagnostics; Cell Biology; Standards and Reference Materials; Inorganic Compounds and Salts; Proteomics; High Purity Biochemical Reagents; Foaming Agents; Excipients; Food Additives; Industrial Surfactants ;Anionic surfactants;Surfactants;Protein detection;Pharmaceutical excipients;Inorganic salts;Inorganic acids;Monomer fragrances;Reference substances;Chemical reagents;Biological buffer series

Introduction

Sodium Lauryl Sulfate is an anionic surfactant, which is a typical representative of sulfate ester surfactants, referred to as SDS, also known as AS, K12, Sodium Coco Sulfate, Sodium Lauryl Sulfate, foaming agent, market The products sold on the market are usually white to slightly yellow crystalline powder, non-toxic, slightly soluble in alcohol, insoluble in chloroform and ether, easily soluble in water, and have good compatibility with anions and non-ions, and have good emulsifying and foaming properties. It has high stability, foaming, penetrating, decontamination and dispersing properties, rich foam and fast biodegradation, but its water solubility is inferior to that of fatty alcohol polyoxyethylene ether sulfate (AES for short). It is not sensitive to alkali and hard water, but its stability is inferior to that of general sulfonates under acidic conditions, close to AES, and long-term heating should not exceed 95 °C. It is higher than AES and lower than sodium dodecylbenzenesulfonate (LAS). Toxicity LD50 is 1300mg/kg. At present, there is no evidence that this product is carcinogenic, and high doses may indeed irritate the skin. However, when it is used as a foaming agent in general bathroom products, the concentration is limited, and it is in line with the standards of various countries in the world, so you don't have to worry.
Sodium lauryl sulfate is the main ingredient in detergents. Commonly used in DNA extraction processes to separate proteins from DNA after denaturation. Often misread as sodium dodecyl sulfonate. As a foaming agent, it is widely used in toothpaste, soap, body wash, shampoo, washing powder, and cosmetics. Sodium lauryl sulfate is found in 95% of personal skin care and household cleaning products.

Chemical properties

Use

●  Sodium lauryl sulfate has excellent decontamination, emulsifying and foaming power, can be used as detergent and textile auxiliary, also used as anionic surfactant, toothpaste foaming agent, mine fire extinguishing agent, foaming of fire extinguisher agent, emulsion polymerization emulsifier, emulsifying and dispersing agent for medicine, cosmetic products such as shampoo, wool detergent, detergent for fine silk and wool fabrics. Flotation agent for metal beneficiation.

●  GB 2760-96 stipulates that it is a processing aid for food industry. Foaming agent; emulsifier; anionic surfactant. For cakes, beverages, protein, fresh fruit, fruit juice drinks, edible oil, etc.

●  1. Surfactant, decontamination, foaming, wetting agent, etc.
2. Compared with low-level ion-pairing reagents, when the requirements are not high, they are cheaper than heptane and sodium pentane sulfonate
3. As raw material, modification of material
4. Capillary electrophoresis analysis, additives, generally used in molar solutions
5. Other analytical methods will also be used, such as flow column analysis.

●  It is used as washing and textile auxiliaries, also used as toothpaste foaming agent, fire extinguishing foam liquid, emulsion polymerization emulsifier, emulsification and dispersing agent for medicine, cosmetic products such as shampoo, wool detergent.

●  1. Surfactants, decontamination, foaming, wetting agents, etc.

2. Relatively low-level ion-pair reagents are cheaper than heptane and sodium pentane sulfonate when the requirements are not high.

3. As a raw material, the modification of materials

4, capillary electrophoresis analysis, additives, generally used in molar solution

5, other analysis methods will also be used, such as flow column analysis.

●  Biochemical Analysis, Electrophoresis, Ion Pairing Reagents

Production method

●  Lauryl sulfate is formed by sulfation of dodecanol and chlorosulfonic acid at 40～50℃, neutralized with sodium hydroxide, bleached, settled and spray-dried.

●  Dodecanol and chlorosulfonic acid are charged in a molar ratio of 1:1.03, and the sulfonation reaction is carried out at 30-35 ° C. The generated sulfonate is neutralized with 30% sodium hydroxide to generate sodium dodecyl sulfate, which is bleached with hydrogen peroxide. , spray drying to get the finished product. Raw material consumption (kg/t) lauryl alcohol (C12>85%) 725 solid base (NaOH>95%) 183 chlorosulfonic acid (>95%) 458

●  There are many preparation methods of sodium lauryl sulfate, the most commonly used are the following two.
The sulfur trioxide method reaction device is a vertical reactor. Nitrogen was introduced into the reactor through a gas vent at 32°C. The nitrogen flow rate was 85.9 L·min-1. Lauryl alcohol was introduced at 82.7 kPa with a flow rate of 58 g·min-1. The liquid sulfur trioxide was passed into the flasher at 124.1 kPa, the flash temperature was maintained at 100 °C, and the flow rate of sulfur trioxide was controlled at 0.907 2 kg·h-1. Then, the sulfated product was rapidly quenched to 50°C, put into an aging device, and placed for 10-20min. Finally, put it into the neutralization kettle and neutralize it with alkali. The neutralization temperature is controlled at 50°C, and when the pH value reaches 7-8.5, the material is discharged to obtain a liquid finished product. Spray-dried to obtain a solid finished product.
Chlorosulfonation
Batch method Put lauryl alcohol into the reactor and preheat to 30℃. Then, 0.03 mol excess of chlorosulfonic acid over the theoretical amount was sprayed into the alcohol in the form of a mist under high-speed stirring. The reaction temperature was controlled at 30-35°C. After the sulfation reaction is completed, it is pumped into a neutralizer and neutralized to pH 7-8.5 with 30% lye. Finally bleached with 0.4% (mass) hydrogen peroxide. Spray dried to give a solid. It can also be formulated into solutions according to quality standards.
The continuous process reaction device is a tubular reactor. The lauryl alcohol is first saturated with hydrogen chloride. Lauryl alcohol entered the saturation chamber through the meter at a flow rate of 334 g·min-1 and hydrogen chloride at a flow rate of 40.5 g·min-1. Then a solution of lauryl alcohol in hydrogen chloride was passed into the reactor at 21.4°C to react with chlorosulfonic acid. After the reactants are separated by gas and liquid, the sulfated product flows into the neutralization kettle from the bottom of the separator. Neutralize with 30% sodium hydroxide at 50°C to obtain a liquid product. A solid product was obtained by spray drying.

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