CAS number：96684-39-8
molecular formula：C57H83N3O39S
molecular weight：1466.33
EINECS number：1312995-182-4

English synonyms

beta-Cyclodextrin, compd. with 4-hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide;Chf 1194;Chf-1194;PiroxicaM-beta-cyclodextrin coMplex;Cycladol;(3E)-3-[hydroxy(pyridin-2-ylam;β-Cyclodextrin,compd.with4-hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide1,1-dioxide;PiroxicaM-β-cyclodextrin coMplex

Related categories

Raw materials; pharmaceutical raw materials; cyclodextrin inclusion compound; raw materials; medical raw materials; raw materials; pharmaceutical raw materials; chemical raw materials; food additives; food additives; organic chemicals

Introduction

Piroxicam-beta-cyclodextrin (also known as piroxicam-beta-cyclodextrin) adopts a unique process route to refine pharmaceutical-grade piroxicam and pharmaceutical-grade beta-cyclodextrin in a certain proportion. to make.
Piroxicam belongs to a kind of non-steroidal anti-inflammatory drugs. It has strong anti-inflammatory effect, but it is insoluble in water and absorbs slowly. It is easy to cause gastrointestinal bleeding and gastric ulcer after oral administration. Intramuscular injection may cause pain and mild pain at the injection site. Degree of tissue necrosis. After the piroxicam is prepared into a piroxicam-β-cyclodextrin (piroxicam-β-cyclodextrin) inclusion complex, the dissolution rate of the drug can be accelerated and the irritation to the gastrointestinal tract can be reduced. Oral analgesic Xilaitong (cycladol) is the successful application of piroxicam-β-cyclodextrin inclusion complex.

Use

●  Piroxicam-beta-cyclodextrin (also known as piroxicam-beta-cyclodextrin) is made by adopting a unique process route and refining pharmaceutical-grade piroxicam and pharmaceutical-grade beta-cyclodextrin in a certain proportion. Compared with piroxicam monomer, this clathrate has lower odor, stronger stability, and more stable drug release rate, etc. It is mainly used in anti-inflammatory and analgesic agents and pharmaceutical excipients.

Team Presentation