Resveratrol CAS 501-36-0
——————
CAS number ： 501-36-0
molecular formula : C14H12O3
EINECS ： 610-504-8
——————
Email ： info@deshangchem.com
Mobile : +86-13153039501
TEL ： +86-531-88752665
CAS number：501-36-0
molecular formula：C14H12O3
molecular weight：228.24
EINECS number：610-504-8
English synonyms
TRANS-3,4,5-TRIHYDROXYSTILBENE;TRANS-3,5,4'-STILBENETRIOL;TRANS-RESVERATROL;TRANS-1,2-(3,4',5-TRIHYDROXYDIPHENYL)ETHYLENE;RESVERATROL;RESVERATROLE;3,4',5'-TRIHYDROXY-TRANS-STILBENE;3,4',5-TRIHYDROXY-TRANS-STILBENE
Related categories
Natural products; other oxygenated compounds; chemical raw materials; analytical standards; plant extracts; reference substances, standard substances; Chinese medicine reference substances; standard substances; organic raw materials; reference substances; Pharmaceuticals and biochemicals; APIs; Standard Chinese medicines; Compounds; Chinese medicine extracts; Biochemical reagents; High-purity plant extracts; Cosmetic raw materials - whitening agents; Chemical reagents; Medical raw materials; Plant component monomers; Intermediates; Standard extracts ;Chemical Products-Organic Chemicals;Biochemical Reagents-Other Chemical Reagents;Reagents;Plant Extracts;Resveratrol;Antibiotics;Other Scientific Research APIs;Pharmaceutical Intermediates;Phenol;Raw Materials;Small Molecule Inhibitors;Small Molecule Inhibitors,Natural Products; pharmaceutical raw materials; pharmaceutical raw materials; standard products; chemical products; medical raw materials; new products; standard products, reference substances; standard products-standard products of traditional Chinese medicine; other phenols; Pesticide and dye intermediates; cosmetic raw materials; main recommended products; other raw materials; fungicides; organic chemical raw materials; high-content monomers; extracts; organic intermediates; food additives; plant extracts; reagents; daily chemicals; antioxidants ;Other products;Biochemicals;High content products;Standard extracts;Monomer fragrances;Research raw materials;Chemical reagents;Cosmetics;Stilbenes (substituted);Miscellaneous;Antioxidant;Biochemistry;Stilbenes;Natural Plant Extract;Beauty;The group of Polydatin;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Caspases/Apoptosis;Health supplements;Plant extracts;Inhibitor;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;natural product ;Pyridines;RESVEPURE;plant extract;501-36-0
Introduction
Resveratrol is a natural antioxidant that reduces blood viscosity, inhibits platelet aggregation and vasodilation, keeps blood flowing, prevents the occurrence and development of cancer, has anti-atherosclerosis and coronary heart disease, ischemic Prevention and treatment of heart disease and hyperlipidemia. The tumor-inhibiting effect also has estrogen-like effects and can be used to treat diseases such as breast cancer. It can delay aging, prevent cancer, and is found in high levels in red grape skins, red wine and grape juice. Studies have shown that the integrity of chromosomes is destroyed as humans age, and resveratrol can activate a protein sirtuin that repairs chromosome health, thereby delaying aging.
Chemical properties
| Melting point | 253-255°C |
| Boiling point | 449.1±14.0 °C(Predicted) |
| Density | 1.359±0.06 g/cm3(Predicted) |
| Storage conditions | -20°C |
| Solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml). |
| Acidity coefficient(pKa) | 9.22±0.10(Predicted) |
| Shape | Powder |
| Colo | Off-white |
| Water solubility | Soluble in water (3 mg/100mL), ethanol (50 mg/mL), DMSO (16 mg/mL), DMF (~65 mg/mL), PBS (pH 7.2) (~100µg/mL), methanol, and acetone (50 mg/mL). |
Merck | 14,8158 |
| Stability | Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
InChIKey | LUKBXSAWLPMMSZ-OWOJBTEDSA-N |
| CAS database | 501-36-0(CAS DataBase Reference) |
Odorless, white powder, completely soluble in ethanol.
Use
● It can prevent the oxidation of low-density lipoprotein, and has the potential to prevent and treat cardiovascular disease, cancer, virus and immune regulation. Its effect is mainly manifested in its antioxidant properties.
● Cardiovascular drugs can lower blood lipids, prevent heart disease, and have anti-AIDS effects
● Antioxidant, with anti-inflammatory, antithrombotic, anticancer, anticancer, antihyperlipidemic, antibacterial and other activities
● Delay aging, regulate blood lipids, protect cardiovascular and cerebrovascular, anti-hepatitis
● Acts as a selective inhibitor of COX?1; a phenolic phytoalexin found in grape skins and other plants, has intracellular antioxidant activity and activates SIRT1; an NAD+-dependent histone deacetylase, contained in mitochondria and enhances peroxisome gamma-activated proliferator co-activator-1α (PGC-1α) and FOXO activity; the antidiabetic, neuroprotective, and fat-suppressing behavior of resveratrol may be mediated through SIRT1 activation contributes to
● COX-1 selective inhibitor. Resveratrol is a phenolic phytoalexin found in grape skins and other plants. It has intracellular antioxidant activity by activating the sirtuin SIRT1. The antidiabetic, neuroprotective, and antilipidemic properties of resveratrol may all be due to the activation of the sirtuin SIRT1.
Production method
● Resveratrol is an inhibitor of oxidative metabolic enzymes of many aromatic carcinogens, and is rated as a natural chemopreventive agent for heart, cerebrovascular diseases and cancer. Numerous studies have shown that resveratrol also has anti-mutagenic activity, protects against cytotoxic effects induced by oxidized lipoproteins, and inhibits the proliferation of tumor cells.
In 1940, humans first isolated resveratrol from the roots of Veratrum grandiflorum, and it has been found in at least 72 species of 21 families and 31 genera, such as Vitis vinifera, Serpentine Vitis, and Leguminosae. Arachis genus, Cassia genus, Sophora genus, Polygonum genus of Polygonaceae, etc. Because the content of resveratrol in plants is very low and the extraction cost is high, the preparation of resveratrol by chemical, biological, genetic engineering and other methods has become an indispensable means in its development process.
Resveratrol CAS 501-36-0
CAS number：501-36-0
molecular formula：C14H12O3
molecular weight：228.24
EINECS number：610-504-8
English synonyms
TRANS-3,4,5-TRIHYDROXYSTILBENE;TRANS-3,5,4'-STILBENETRIOL;TRANS-RESVERATROL;TRANS-1,2-(3,4',5-TRIHYDROXYDIPHENYL)ETHYLENE;RESVERATROL;RESVERATROLE;3,4',5'-TRIHYDROXY-TRANS-STILBENE;3,4',5-TRIHYDROXY-TRANS-STILBENE
Related categories
Natural products; other oxygenated compounds; chemical raw materials; analytical standards; plant extracts; reference substances, standard substances; Chinese medicine reference substances; standard substances; organic raw materials; reference substances; Pharmaceuticals and biochemicals; APIs; Standard Chinese medicines; Compounds; Chinese medicine extracts; Biochemical reagents; High-purity plant extracts; Cosmetic raw materials - whitening agents; Chemical reagents; Medical raw materials; Plant component monomers; Intermediates; Standard extracts ;Chemical Products-Organic Chemicals;Biochemical Reagents-Other Chemical Reagents;Reagents;Plant Extracts;Resveratrol;Antibiotics;Other Scientific Research APIs;Pharmaceutical Intermediates;Phenol;Raw Materials;Small Molecule Inhibitors;Small Molecule Inhibitors,Natural Products; pharmaceutical raw materials; pharmaceutical raw materials; standard products; chemical products; medical raw materials; new products; standard products, reference substances; standard products-standard products of traditional Chinese medicine; other phenols; Pesticide and dye intermediates; cosmetic raw materials; main recommended products; other raw materials; fungicides; organic chemical raw materials; high-content monomers; extracts; organic intermediates; food additives; plant extracts; reagents; daily chemicals; antioxidants ;Other products;Biochemicals;High content products;Standard extracts;Monomer fragrances;Research raw materials;Chemical reagents;Cosmetics;Stilbenes (substituted);Miscellaneous;Antioxidant;Biochemistry;Stilbenes;Natural Plant Extract;Beauty;The group of Polydatin;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Caspases/Apoptosis;Health supplements;Plant extracts;Inhibitor;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;natural product ;Pyridines;RESVEPURE;plant extract;501-36-0
Introduction
Resveratrol is a natural antioxidant that reduces blood viscosity, inhibits platelet aggregation and vasodilation, keeps blood flowing, prevents the occurrence and development of cancer, has anti-atherosclerosis and coronary heart disease, ischemic Prevention and treatment of heart disease and hyperlipidemia. The tumor-inhibiting effect also has estrogen-like effects and can be used to treat diseases such as breast cancer. It can delay aging, prevent cancer, and is found in high levels in red grape skins, red wine and grape juice. Studies have shown that the integrity of chromosomes is destroyed as humans age, and resveratrol can activate a protein sirtuin that repairs chromosome health, thereby delaying aging.
Chemical properties
| Melting point | 253-255°C |
| Boiling point | 449.1±14.0 °C(Predicted) |
| Density | 1.359±0.06 g/cm3(Predicted) |
| Storage conditions | -20°C |
| Solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml). |
| Acidity coefficient(pKa) | 9.22±0.10(Predicted) |
| Shape | Powder |
| Colo | Off-white |
| Water solubility | Soluble in water (3 mg/100mL), ethanol (50 mg/mL), DMSO (16 mg/mL), DMF (~65 mg/mL), PBS (pH 7.2) (~100µg/mL), methanol, and acetone (50 mg/mL). |
Merck | 14,8158 |
| Stability | Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
InChIKey | LUKBXSAWLPMMSZ-OWOJBTEDSA-N |
| CAS database | 501-36-0(CAS DataBase Reference) |
Odorless, white powder, completely soluble in ethanol.
Use
● It can prevent the oxidation of low-density lipoprotein, and has the potential to prevent and treat cardiovascular disease, cancer, virus and immune regulation. Its effect is mainly manifested in its antioxidant properties.
● Cardiovascular drugs can lower blood lipids, prevent heart disease, and have anti-AIDS effects
● Antioxidant, with anti-inflammatory, antithrombotic, anticancer, anticancer, antihyperlipidemic, antibacterial and other activities
● Delay aging, regulate blood lipids, protect cardiovascular and cerebrovascular, anti-hepatitis
● Acts as a selective inhibitor of COX?1; a phenolic phytoalexin found in grape skins and other plants, has intracellular antioxidant activity and activates SIRT1; an NAD+-dependent histone deacetylase, contained in mitochondria and enhances peroxisome gamma-activated proliferator co-activator-1α (PGC-1α) and FOXO activity; the antidiabetic, neuroprotective, and fat-suppressing behavior of resveratrol may be mediated through SIRT1 activation contributes to
● COX-1 selective inhibitor. Resveratrol is a phenolic phytoalexin found in grape skins and other plants. It has intracellular antioxidant activity by activating the sirtuin SIRT1. The antidiabetic, neuroprotective, and antilipidemic properties of resveratrol may all be due to the activation of the sirtuin SIRT1.
Production method
● Resveratrol is an inhibitor of oxidative metabolic enzymes of many aromatic carcinogens, and is rated as a natural chemopreventive agent for heart, cerebrovascular diseases and cancer. Numerous studies have shown that resveratrol also has anti-mutagenic activity, protects against cytotoxic effects induced by oxidized lipoproteins, and inhibits the proliferation of tumor cells.
In 1940, humans first isolated resveratrol from the roots of Veratrum grandiflorum, and it has been found in at least 72 species of 21 families and 31 genera, such as Vitis vinifera, Serpentine Vitis, and Leguminosae. Arachis genus, Cassia genus, Sophora genus, Polygonum genus of Polygonaceae, etc. Because the content of resveratrol in plants is very low and the extraction cost is high, the preparation of resveratrol by chemical, biological, genetic engineering and other methods has become an indispensable means in its development process.
Team Presentation
Firm：Shandong Deshang Chemical Co., LTD
Phone
：+86-13153039501
Email
：info@deshangchem.com
Add：11th Floor, Chuangbo Industrial Park, 177 Tianchen Road, High-tech Zone, Jinan City, Shandong Province, China
Linke：