English synonyms

Radix Scutellariae;Scutellaria baicalensis Grorgi. Extract;BaikalSkullcapRoot.P.E;Baical Skullcap Root Extract;Scutellaria root extract;Baicalin P.E;Baical Skullcap root P.E;Baicalin Extract

Related categories

PCR kit; dye-based fluorescent quantitative PCR kit; PCR kit-probe fluorescent quantitative PCR kit; standard extract; standard product; plant extract; Chinese herbal medicine components; Natural Whole Herb Essential Oils

Introduction

Scutellaria baicalensis extract is derived from the dry root of Scutellaria baicalensis Georg, a plant of the Labiatae family. Scutellaria baicalensis is a commonly used traditional Chinese medicine, mainly produced in the north, and Shanxi Province has the largest output. Also known as camellia root and earth gold tea root, it has the functions of clearing away heat, detoxifying, and stopping bleeding.

Chemical properties

Light yellow crystalline powder, melting point 223°C-225°C, hardly soluble in ethanol, methanol, acetone, slightly soluble in chloroform and nitrobenzene, almost insoluble in water, soluble in hot acetic acid, etc.

Use

●  The traditional Chinese medicine Scutellaria baicalensis has the effects of clearing away heat, detoxifying, stopping bleeding, and preventing miscarriage. It is mainly used for dampness and temperature caused by damp heat, jaundice, diarrhea, hot stranguria, pain, swelling and sores. It is also used for lung heat, cough, fetal movement, and internal heat. Hematemesis, hemoptysis, epistaxis, hematochezia, and metrorrhagia caused by forcing blood.

●  Modern pharmacological studies have proved that Scutellaria baicalensis has a wide range of antibacterial effects, has antibacterial effects on common bacteria, has the strongest inhibitory effect on Staphylococcus aureus and Pseudomonas aeruginosa, and has obvious sedative, antipyretic, and anti-inflammatory effects.

●  Tobacco spices: increase aroma, soft smoke, clean aftertaste, it is a kind of natural flavor with stable quality.

●  Scutellaria baicalensis extract is a class of flavonoids extracted and isolated from Scutellaria baicalensis root, which has significant biological activity, antibacterial, diuretic, anti-inflammatory, anti-allergic and antispasmodic effects, and has strong anti-cancer response and other physiological functions. efficacy. In addition, the active ingredient baicalin in the Scutellaria baicalensis extract can also absorb ultraviolet rays, scavenge oxygen free radicals, and inhibit the formation of melanin, so it can be used in both medicine and cosmetics, and is a good functional whitening cosmetic raw material.

●  In the 06th issue of "Inner Mongolia Medical Journal" in 2014, the in vitro Oxford cup drug sensitivity method and the intraperitoneal injection of mice were used to observe the antibacterial effect of Scutellaria baicalensis extract. The alcohol extract of Scutellaria baicalensis has better antibacterial effect in vitro, while the aqueous extract of Scutellaria baicalensis has no inhibitory effect on Staphylococcus aureus in vitro. The antibacterial effect of Scutellaria baicalensis alcohol extract in vivo is not as good as Scutellaria baicalensis water extract.

●  It is mainly used to treat hepatitis in China, and has obvious curative effects on acute jaundice, acute anicteric and chronic hepatitis. In addition, studies have shown that the extract of Scutellaria baicalensis can be used as a drug against Japanese encephalitis virus.

●  Baicalin has a relieving effect on the allergic contraction of isolated trachea of guinea pigs and the allergic asthma of the whole animal, and it is synergistic with ephedrine. The phosphate of aglycone has a stronger effect than sodium sulfate. Baicalin can inhibit the Schul-tz-Dale reaction of the isolated trachea and ileum, and it can also inhibit the passive skin allergic reaction and histamine skin reaction of guinea pigs. On the one hand, aglycones are stronger than glycosides. The anti-allergic reaction of Scutellaria baicalensis is due to the damage to the enzyme activation system of mast cells and the inhibition of the release of allergic mediators, so that no allergic reactions occur. In addition, it also has a direct relaxation effect on smooth muscle itself. Both baicalin and baicalin can inhibit allergic edema and inflammation, both can reduce the permeability of mouse ear capillaries, and the latter can still prevent low air pressure from causing pulmonary hemorrhage in mice.

●  Scutellaria baicalensis has a wide antibacterial spectrum, and it has inhibitory effects on Shigella, diphtheria bacillus, Pseudomonas aeruginosa, staphylococcus, streptococcus, pneumococcus and meningococcus in test tubes. Carriers are also effective, even Staphylococcus aureus, which has developed resistance to penicillin, is still sensitive to Scutellaria baicalensis. It has inhibitory effect on in vitro tuberculosis, and the reports are different. The decoction is effective on experimental tuberculosis in mice, but not on guinea pigs. It has inhibitory effect on PR8 strain of influenza virus in test tube, and can reduce lung damage and prolong survival time after mice are infected with the virus. It also has inhibitory effect on a variety of skin-pathogenic fungi in vitro and can kill Leptospira.

Production method

●  The optimal process of the Scutellaria baicalensis extract is as follows: reflux extraction with eight times the amount of 70% ethanol for 3 times, each time for 2 hours, combine the filtrates, concentrate under reduced pressure to 100mL, extract 3 times with an equal volume of petroleum ether, take the alcohol-soluble components and use normal Extract with butanol, concentrate the alcohol layer separately, and concentrate under reduced pressure to a density of (1.013±0.004) g/cm3.

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