CAS number：41194-16-5
molecular formula：C21H43N5O15S
molecular weight：637.66
EINECS number：687-974-6

English synonyms

APRAMYCIN SULPHATE;5-AMINO-2-[[9-AMINO-8-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXOXY)-5-HYDROXY-4-METHYLAMINO-2,7-DIOXABICYCLO[4.4.0]DEC-3-YL]OXY]-6-(HYDROXYMETHYL)OXANE-3,4-DIOL;ApramycinSulphateCp2003;5-Amino-2-[[9-amino-8-(4,6-diamino-2,3-dihydroxy-cyclohexoxy)-5-hydroxy-4-methylamino-2,7-dioxabicyclo[4.4.0]dec-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4-diol sulfate;Apramycin sulfate;NEBRAMYCIN 11 SULPHATE;NEBRAMYCIN II;NEBRAMYCIN II SULFATE

Related categories

Antibiotics; Raw Materials; Pharmaceutical Raw Materials; Aminocycloalcohol Antibiotics; Raw Material Intermediates-APIs; Veterinary Drug Raw Materials; Intermediates; Chemical Industry; Veterinary Raw Materials; Raw Materials; Additives; Chemical Materials; Chemical Reagents; Medical Raw Materials; ;Antibiotics;Veterinary Raw Materials;Chemical Raw Materials;Industrialization

Introduction

Apramycin Sulfate is yellow or tan powder, hygroscopic and easily soluble in water. Apramycin sulfate can be used to prevent and treat bacterial diarrhea and is an excellent drug.

Use

●  For the treatment of piglet dysentery

●  It is mainly used to treat porcine colibacillosis and other diseases caused by sensitive bacteria. It can also treat diarrhea caused by Enterobacter calf and Salmonella. It is also effective against Escherichia coli, Salmonella and some mycoplasma infections in chickens.

●  The product has extremely low toxicity, is better absorbed in the digestive tract, can be evenly distributed in various tissues, and can be transferred to livestock and poultry products. In feed additives, it is often used in combination with lincomycin, which is effective in the prevention and treatment of chicken mycoplasma <mycoplasma> disease; it has special effects on pig diarrhea.

Production method

API Active Pharmaceutical Ingredients
Obtained from natural medicine. Natural medicine is an important part of medicine. For example, artemisinin, an effective antimalarial ingredient isolated from the traditional Chinese medicine Artemisia annua.
Take existing drugs as first-comers.
1) Discover the active ingredients of the drug from the side effects of the drug. For example, the phenothiazine antipsychotic chlorpromazine and its analogs are developed from the sedative side effects of the similarly structured antihistamine promethazine.
2) Obtained through drug metabolism research. For example, the metabolites of antidepressants imipramine and amitriptyline, norimipramine and noramitriptyline, have stronger antidepressant effects than the original drug; oxazepam is the active metabolite of diazepam.
3) Leading with existing breakthrough drugs. For example, the research on lansoprazole and other prazols is based on omeprazole, which is more active than omeprazole.
Obtained by screening with pharmacological model. Through combinatorial chemistry, a large number of chemical libraries with different structures are constructed without separation of mixtures. Through high-throughput screening, the components are found to have pharmaceutical activity and then separated, and the structure of the active compound is determined.
Designed according to physiological and pathological mechanisms. For example: the study of fluorouracil takes the nucleotide uracil synthesized from DNA or RNA as the lead compound, and replaces the hydrogen at position 5 with fluorine, making it a metabolic antagonist of the normal metabolites of the organism, and is used as an antitumor drug

Team Presentation